Scientists have released a landmark map of gene activity in the human brain that holds clues to Alzheimer's disease.

The work includes single-nucleus atlases and high-resolution molecular maps of the prefrontal cortex.

Researchers used advanced sequencing to map gene activity at very fine cellular resolution, the article says.

The maps show how genetic regulation works within specific types of brain cells.

The research appears in a coordinated collection of papers from multiple institutions.

The article says nine studies in the collection were led by Mount Sinai investigators.

The National Institutes of Health and academic teams supported the investigations.

Labs are already using the atlas to pinpoint cell pathways linked to cognitive decline, the piece reports.

Future work aims to expand samples across diverse patients and track molecular changes over time.

Read the full article on the new brain gene activity map and Alzheimer's research.