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Tuesday, January 14, 2025

New drugs for migraines as effective as cheap painkillers

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Migraine headaches can be debilitating for those who suffer from them, impacting their quality of life and ability to function normally. In the past, traditional painkillers were often the go-to treatment for migraines. However, a recent study has found that newer, more expensive drugs can be just as effective in treating migraines as these cheaper options.

The study, published in JAMA Internal Medicine, compared the effectiveness of newer migraine drugs known as calcitonin gene-related peptide (CGRP) monoclonal antibodies with traditional painkillers such as ibuprofen and acetaminophen. The researchers found that the CGRP monoclonal antibodies were just as effective at relieving migraine symptoms as the cheaper painkillers.

This is significant because CGRP monoclonal antibodies are a newer class of drugs specifically designed to target the pathways in the brain that are involved in migraine attacks. These drugs are administered as injections or infusions and work by blocking the action of CGRP, a molecule that is involved in the transmission of pain signals in the brain.

The study involved over 1,200 participants who suffered from episodic migraines, meaning they experienced less than 15 migraine days per month. The participants were randomly assigned to receive either a CGRP monoclonal antibody or a traditional painkiller to treat their migraines.

After 12 weeks of treatment, the researchers found that both groups experienced a similar reduction in the frequency and severity of their migraine attacks. This suggests that the newer, more expensive CGRP monoclonal antibodies are just as effective at treating migraines as the cheaper painkillers.

These findings have important implications for the treatment of migraines, as they suggest that newer drugs may offer a more targeted and effective treatment option for migraine sufferers. While traditional painkillers can be effective for some people, they may not work for everyone and can have side effects with long-term use.

It’s important to note that CGRP monoclonal antibodies are currently only available by prescription and can be expensive. However, for those who have not found relief with traditional painkillers or are looking for a more targeted treatment option, these newer drugs may be worth considering.

In conclusion, the results of this study suggest that newer drugs for migraines, such as CGRP monoclonal antibodies, can be just as effective as cheap painkillers in relieving migraine symptoms. This research provides hope for migraine sufferers who have been searching for more targeted and effective treatment options. It’s important to consult with a healthcare provider to determine the best treatment approach for your individual needs.

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